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Congress
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Plenary Session 3203

Protein Aggregate Clearance in Aging and Neurodegeneration: From Pathways to Therapies

Tuesday, October 7, 2025
8:00 - 9:30 | Room TBD
Translational

In this session, the faculty will describe mechanisms of protein aggregate clearance in aging and neurodegeneration, how protein aggregation drives progression and how this knowledge can be translated into new therapeutic approaches.


Chairs:
Gabor Kovacs, Canada
Tiago Outeiro, Germany

Presenters:

Waste Clearance and the Aging Brain
Roxana Carare, United Kingdom

The Role of Protein Aggregation on Disease Progression
TBD

Therapeutic Strategies Targeting Protein Aggregation
TBD

CSPC Liaisons:
Gabor Kovacs, Canada

Learning Objectives
At the conclusion of this session, participants should be better able to:

  1. Identify the waste clearance mechanisms of the human brain in aging including glymphatics
  2. Summarize evidence that multiple protein aggregation and propagation drives progression in neurodegenerative disease
  3. Identify major therapeutic strategies targeting protein aggregates clearance

Recommended Audience
Clinician / General Neurology
Fellow / Resident / Student
Health Professional (non-physician)
Industry
Researcher / Basic Science

Education Level
Advanced / Expert
Beginner / Foundational
Intermediate / Experienced

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